*rankings updated November 17, 2008
Tyson Jackson - LSU Everson Griffen - USC
$$ - Foregoing remaining eligibility to enter draft.
| Rank | Name | College | Ht. | Wt. | 40 | Class |
| 1. | Everson Griffen | USC | 6-3 | 265 | 4.54 | Sophomore |
| 2. | Tyson Jackson | LSU | 6-5 | 292 | 4.88 | Senior |
| 3. | Michael Johnson | Georgia Tech | 6-7 | 260 | 4.64 | Senior |
| 4. | George Selvie | South Florida | 6-4 | 242 | 4.69 | Junior |
| 5. | Brian Orakpo | Texas | 6-4 | 260 | 4.72 | Senior |
| 6. | Greg Hardy | Mississippi | 6-4 | 265 | 4.83 | Junior |
| 7. | Everette Brown | Florida State | 6-4 | 248 | 4.66 | Junior |
| 8. | Da'Quan Bowers | Clemson | 6-5 | 265 | 4.66 | Freshman |
| 9. | Jerry Hughes | TCU | 6-2 | 260 | 4.77 | Junior |
| 10. | Maurice Evans | Penn State | 6-2 | 264 | 4.75 | Junior |
| 11. | Brandon Graham | Michigan | 6-2 | 270 | 4.83 | Junior |
| 12. | Auston English | Oklahoma | 6-3 | 253 | 4.76 | Junior |
| 13. | Matt Shaughnessy | Wisconsin | 6-6 | 253 | 4.77 | Senior |
| 14. | Ricky Sapp | Clemson | 6-4 | 240 | 4.66 | Junior |
| 15. | Greg Middleton | Indiana | 6-3 | 275 | 4.91 | Junior |
| 16. | Carlos Dunlap | Florida | 6-6 | 290 | 4.65 | Sophomore |
| 17. | Derrick Morgan | Georgia Tech | 6-4 | 270 | 4.77 | Sophomore |
| 18. | Connor Barwin | Cincinnati | 6-4 | 240 | 4.73 | Senior |
| 19. | Aaron Maybin | Penn State | 6-4 | 245 | 4.66 | Sophomore |
| 20. | Barry Turner | Nebraska (Out for Season) | 6-3 | 265 | 4.53 | Senior |
| 21. | Tim Jamison | Michigan | 6-3 | 263 | 4.93 | Senior |
| 22. | Antonio Coleman (DE/OLB) | Auburn | 6-2 | 250 | 4.72 | Junior |
| 23. | Kyle Moore | USC | 6-6 | 270 | 4.73 | Senior |
| 24. | Jermaine Cunningham (DE/OLB) | Florida | 6-3 | 250 | 4.68 | Junior |
| 25. | Larry English (DE/OLB) | Northern Illinois | 6-3 | 254 | 4.76 | Senior |
| 26. | Cody Brown | Connecticut | 6-3 | 246 | 4.69 | Senior |
| 27. | Henry Melton | Texas | 6-3 | 265 | 4.78 | Senior |
| 28. | Cliff Matthews | South Carolina | 6-4 | 250 | 4.69 | Sophomore |
| 29. | Brandon Harold | Kansas State | 6-6 | 264 | 4.77 | Freshman |
| 30. | Lawrence Wilson | Ohio State (Out for Season) | 6-4 | 274 | 4.72 | Junior |
| 31. | Dexter Davis (DE/OLB) | Arizona State | 6-2 | 252 | 4.69 | Junior |
| 32. | Marcus Tillman | Mississippi | 6-4 | 260 | 4.75 | Junior |
| 33. | Thaddeus Gibson | Ohio State | 6-2 | 240 | 4.59 | Sophomore |
| 34. | Nick Reed | Oregon | 6-2 | 255 | 4.87 | Senior |
| 35. | Eddie Jones | Texas | 6-3 | 260 | 4.74 | Sophomore |
| 36. | Jeff Schweiger | San Jose State | 6-5 | 255 | 4.63 | Senior |
| 37. | Ugo Chinasa | Oklahoma State | 6-6 | 255 | 4.72 | Sophomore |
| 38. | Pannel Egboh | Stanford | 6-6 | 270 | 4.81 | Senior |
| 39. | Derek Walker | Illinois | 6-4 | 270 | 4.81 | Senior |
| 40. | Zach Potter | Nebraska | 6-7 | 280 | 4.88 | Senior |
| 41. | Kirston Pittman | LSU | 6-4 | 254 | 4.76 | Senior |
| 42. | Robert Ayers | Tennessee | 6-3 | 270 | 4.72 | Senior |
| 43. | Jamaal Westerman | Rutgers | 6-3 | 265 | 4.78 | Senior |
| 44. | Willie Young | North Carolina State | 6-4 | 243 | 4.63 | Junior |
| 45. | Robert Rose | Ohio State | 6-5 | 285 | 4.91 | Junior |
| 46. | Derek Burton | Oklahoma State | 6-5 | 265 | 4.68 | Junior |
| 47. | Jeremy Beal | Oklahoma | 6-3 | 253 | 4.77 | Sophomore |
| 48. | Ethan Johnson | Notre Dame | 6-4 | 275 | 4.89 | Freshman |
| 49. | Christian Ballard | Iowa | 6-4 | 284 | 4.77 | Sophomore |
| 50. | Wes Brown | Tennessee | 6-4 | 256 | 4.88 | Junior |
| 51. | Adrian Clayborn | Iowa | 6-3 | 282 | 4.73 | Sophomore |
| 52. | Brandon Deaderick | Alabama | 6-4 | 286 | 5.00 | Junior |
| 53. | Rulon Davis | California | 6-5 | 281 | 4.89 | Senior |
| 54. | Justin Trattou | Florida | 6-3 | 265 | 4.75 | Sophomore |
| 55. | Simi Kuli | Oregon State | 6-4 | 270 | 4.75 | Junior |
| 56. | Courtney Harris | Miami (Fla.) | 6-3 | 255 | 4.71 | Junior |
| 57. | Aaron Lewis | Texas | 6-4 | 265 | 4.68 | Senior |
| 58. | Sam Acho | Texas | 6-3 | 258 | 4.67 | Sophomore |
| 59. | Neefy Moffett | Florida State | 6-1 | 256 | 4.58 | Senior |
| 60. | Antwain Robinson | Arkansas | 6-2 | 258 | 4.78 | Senior |
| 61. | Jan Jorgensen | BYU | 6-3 | 256 | 4.73 | Junior |
| 62. | Stryker Sulak | Missouri | 6-5 | 250 | 4.71 | Senior |
| 63. | Greg Romeus | Pittsburgh | 6-5 | 265 | 4.82 | Sophomore |
| 64. | William VanDeSteeg | Minnesota | 6-4 | 256 | 4.84 | Senior |